What are the stages of kidney insufficiency?
First stage: Compensation period of renal insufficiency: In the first stage of renal insufficiency, the value of serum creatinine ranged from 133 to 177 umol / l. If you have serum creatinine between 133 and 177 umol / l during your physical examination, but your body does not show any symptoms of discomfort, don't think you are in good health. Although the external symptoms of the body did not show up, there was already a problem with the kidneys inside the body. Because the compensatory capacity of the kidney is very high, although renal function has decreased in clinic, its ability to excrete metabolic products and adjust the balance of water and electrolyte can still meet the normal needs.There are no clinical symptoms, and renal function tests are in the normal range or occasionally slightly higher. The second stage of renal insufficiency, kidney insufficiency decompensation phase ( also called renal insufficiency azotemia phase )
The second stage, renal insufficiency decompensation phase: The value of serum creatinine ranged from 177 to 443 umol / l. Glomeruli have more damage, 60 % - 75 %. Kidney begins to fail to excret metabolic waste. Creatinine and urea nitrogen can be higher than normal. The patient suffered from anemia, fatigue, weight loss and difficulty in concentration, which symptoms often ignored. If there is water loss, infection and bleeding, the progress of the disease will be accelerated.
Stage III: renal failure: In the third stage of renal function, the value of serum creatinine ranged from 443 to 707 umol / l. Glomerular sclerosis, renal tubulointerstitial fibrosis and renal vascular fibrosis lead to severe renal function damage, marked anemia, increased nocturia, increased serum creatinine and blood urea nitrogen. And often acidosis, if patients do not receive systematic and regular treatment at this time, they will develop to end-stage renal disease, making treatment more difficult. Renal insufficiency Stage IV, uremia or End Stage Renal Insufficiency
Stage IV: Uremic phase: The value of serum creatinine is greater than 707 umol / l. Glomerular damage has exceeded 95 % in this period, with severe clinical symptoms such as severe nausea, vomiting, low urine, edema, malignant hypertension, severe anemia, and skin pruritus, the mouth being smelled of urine, etc.
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